Source: http://gsegarden.wordpress.com/2013/07/23/wednesday-july-10-2013/
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Wednesday, July 24, 2013
Wednesday, July 10, 2013 | GreenStar Enterprise
[unable to retrieve full-text content]They are offered an opportunity to learn and develop entrepreneurial business skills, and become advocates for environmental and health issues amongst their peers and within their community. The Green Star Enterprise program presents youth from diverse backgrounds the opportunity to learn and ... to participate in self-employment activities centered on environmental themes and community gardening. Promote healthy lifestyle through nutrition and fitness.
2013 Fantasy Football Preview: Wide Receivers
Because the wide receiver spot is often an afterthought in fantasy football due to the depth of the position, it's easy to get lost in filling roster holes. If you are one of those people, take your right hand and slap yourself with it because you are doing a grave injustice to one of the most important positions in fantasy ? if you are a lefty, use your right hand anyway?just because?
In most traditional leagues, you start three wideouts. That's three slots out of (again, average) nine that you submit each week. When you are talking about one-third of your fantasy points a week, you sure as heck better put some thought into exactly who you are putting in those spots before you hit the submit button.
Nugget of insight planted, here are my top 50 wideouts entering the 2013 season.
Hall of Fame Tier
Can't miss studs. Best of the best.
1. Calvin Johnson ? Detroit
122 catches for 1,964 yards in 2012 gets you the top spot in this list. Would like to see more than five touchdowns this season though.
2. A.J. Green ? Cincinnati
3. Dez Bryant ? Dallas
4. Brandon Marshall ? Chicago
In his first season with Chicago, Marshall set career highs with 118 catches, 194 targets and 1,508 yards.
5. Julio Jones ? Atlanta
Pro Bowl Tier
Minimal risk. Will consistently produce at top level.
6. Demaryius Thomas ? Denver
The main question surrounding Thomas is whether new addition Wes Welker will steal some touches away.
7. Andre Johnson ? Houston
8. Percy Harvin ? Seattle
9. Roddy White ? Atlanta
10. Larry Fitzgerald ? Arizona
Although turning 30, Fitzgerald is looking to bounce back from his worst season as a pro. The addition of quarterback Carson Palmer should help this.
11. Wes Welker ? Denver
Going from Tom Brady to Peyton Manning. I can think of worse changes.
12. Randall Cobb ? Green Bay
13. Victor Cruz ? New York Giants
New contract but still the same old complaints. However, if his fellow receiver Hakeem Nicks can stay healthy, indecision from defenses on who to double team should lead to plenty of big games for both.
14. Vincent Jackson -Tampa Bay
15. Marques Colston ? New Orleans
16. Jordy Nelson ? Green Bay
Role Player Tier
Minimal Risk/High Reward
17. Dwayne Bowe ? Kansas City
18. Eric Decker ? Denver
19. James Jones ? Green Bay
20. Hakeem Nicks ? New York Giants
21. Reggie Wayne ? Indianapolis
The Colts are going with a new playbook this season, which hopefully doesn't translate to early season gaffes by the offense. Entering his 13th NFL season, this is only Wayne's third different playbook.
22. Pierre Garcon ? Washington
HR Tier
High Risk/High Reward
23. Cecil Shorts ? Jacksonville
24. Steve Smith ? Carolina
25. Steve Johnson ? Buffalo
26. Danny Amendola ? New England
Amendola will have some big shoes to fill in replacing Wes Welker. Good thing he has Tom Brady throwing him the ball. Trust in the Patriots gift for keeping production with different players when it comes to drafting Amendola.
27. Torrey Smith ? Baltimore
28. Antonio Brown ? Pittsburgh
With Mike Wallace's departure to Miami, the receiving corps is now led by Brown. Until other receivers step up, open looks may be hard to find for this speedster.
29. Mike Williams ? Tampa Bay
30. Mike Wallace ? Miami
31. Tavon Austin ? St. Louis
Rookie receivers traditionally aren't anywhere near to surefire but considering Austin immediately becomes the number one receiving option for the Rams, consider him a safe pick.
32. T.Y. Hilton ? Indianapolis
33. Kenny Britt ? Tennessee
34. Miles Austin ? Dallas
35. Greg Jennings ? Minnesota
Early word out of Vikings camp has quarterback Christian Ponder not turning heads. Lack of a reliable QB could seriously hurt Jennings' production this season.
36. DeSean Jackson ? Philadelphia
37. Lance Moore ? New Orleans
Fringe Tier
Guys with talent that are borderline starters
38. Josh Gordon ? Cleveland
39. Anquan Boldin ? San Francisco
40. Mohamed Sanu ? Cincinnati
41. Emmanuel Sanders ? Pittsburgh
As the number two receiver for the Steelers, Sanders will have both opportunity and the open looks to create some serious numbers this season.
42. DeAndre Hopkins ? Houston
43. Ryan Broyles ? Detroit
44. Sidney Rice ? Seattle
It's put up or shut up time for Rice as he enters the third year of a $41 million, five-year deal. With Golden Tate breathing down his neck and the addition of Percy Harvin, the time is now for Rice.
Spot-Start Tier
Need a start for bye-weeks or injuries then say no more.
45. Alshon Jeffery ? Chicago
46. Brandon LaFell ? Carolina
47. Kendall Wright ? Tennessee
48. Golden Tate ? Seattle
49. Chris Givens ? St. Louis
50. Santonio Holmes ? New York Jets
Because someone has to catch the occasional Sanchez ball in a Jets game other than the other team, Holmes could have some nice numbers at times.
James LeBeau is a contributor for CraveOnline Sports. You can follow him on Twitter @Jlebeau76 or subscribe on Facebook.com/CraveOnlineSports.
Photo Credit: Getty (C. Johnson, A. Johnson), Icon (R. Wayne, T. Austin)
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Ousted Egyptian leader's family denounces military
CAIRO (AP) ? The family of ousted President Mohammed Morsi furiously denounced the military Monday, accusing it of "kidnapping" him, and European diplomats urged that Egypt's first freely elected leader be released after being held incommunicado for nearly three weeks since being deposed by the army.
The fate of Morsi, who has been held without charge, has become a focus of the political battle between his Muslim Brotherhood and the new military-backed government.
The Brotherhood has tried to use Morsi's detention to rally the country to its side, hoping to restore its badly damaged popularity. The interim government, in turn, appears in part to be using it to pressure his supporters into backing down from their protests demanding his reinstatement.
Those protests again turned violent Monday, with clashes breaking out between Morsi supporters and opponents near Cairo's Tahrir Square, and between pro-Morsi demonstrators and police in a city on the capital's northern edge. At least four people were killed.
So far, however, the outcry over Morsi's detention seems to have gained little traction beyond the president's supporters, without bringing significantly greater numbers to its ongoing rallies around the country.
Millions of Egyptians filled the streets starting June 30, demanding the president's removal after a year in office and leading to the coup that ousted him. Anti-Brotherhood sentiment remains strong, further fueled by protests that block traffic in congested city centers and by media that have kept a staunchly anti-Morsi line. Egyptian human rights groups have said he should either be freed or charged.
Behind-the-scenes talks have been taking place through mediators between Brotherhood figures and the interim government ? centered around releasing Morsi and other detained leaders of the group in return for an end to protests by his supporters, according to Mohammed Aboul-Ghar, head of a liberal political party that backed the president's overthrow.
The military fears that Morsi's release "would only increase protests and make them more aggressive," he told The Associated Press. At least five other prominent Brotherhood members have also been detained. The military also has said that there is no way the measures taken against Morsi will be reversed.
The Brotherhood so far seems unlikely to make a deal, saying it cannot accept a military coup. It and other Morsi supporters vow they will not stop protests until he is returned to office, and they have said there will be no negotiations with the new leadership unless it accepts his reinstatement. They have denied any back-channel talks are taking place.
In a toughly worded statement Monday, the Brotherhood laid out a plan for resolving the crisis that was little changed from what Morsi proposed in his final days in office. It said Morsi must first be reinstated along with the now-dissolved upper house of parliament and the suspended constitution, followed by new parliament elections that would start a process for amending the constitution, and then a "national dialogue" could be held.
It denounced those behind Morsi's ouster as "putschists" and accused "coup commanders, with foreign support" of overthrowing "all the hopes in a democratic system."
Interim President Adly Mansour repeated calls for reconciliation in a nationally televised speech Monday evening. "We ... want to turn a new page in the nation's book," he said. "No contempt, no hatred, no divisions and no collisions."
Morsi was detained July 3, when Gen. Abdel-Fattah el-Sissi, the army chief, announced his removal. He is held at an undisclosed location and has had no contact with family or supporters. Government officials have said only that he is safe, is well-cared for and is being held for his own protection.
Two of Morsi's children lashed out at the military over his detention, saying his family has not been permitted to see him since then.
"What happened is a crime of kidnapping," one of his sons, Osama, told a Cairo news conference. "I can't find any legal means to have access to him."
The younger Morsi, who is a lawyer, called his father's detention the "embodiment of the abduction of popular will and a whole nation," and said the family will "take all legal actions" to end his detention.
In a statement read by Morsi's daughter, Shaimaa, the family said it held "the leaders of the bloody military coup fully responsible for the safety and security of the president."
European Union foreign ministers called for the release of Morsi and "all political detainees," saying it was among their key priorities for Egypt's new leadership.
The United States has stopped short of calling for his release. The White House repeated its call Monday for the end of politicized arrests and detentions. But spokesman Jay Carney said of Morsi: "We believe his situation needs to be resolved in a way that is consistent with the rule of law and due process and allows for his personal security."
"This is an issue that goes beyond one individual," he said, adding that resolving Morsi's situation wouldn't end the broader conflict in Egypt.
Prosecutors have said they are investigating allegations that Morsi and Brotherhood officials conspired with the Palestinian militant group Hamas to carry out a 2011 attack on prisons that freed Morsi and other Brotherhood leaders from jail during the 18-day uprising against autocrat Hosni Mubarak.
However, the prosecutors have not formally ordered Morsi detained for investigation, meaning his detention effectively remains outside the legal system.
Prominent rights activist Hossam Bahgat said a coalition of rights groups are preparing a joint call for Morsi to be indicted over the deaths of dozens of Egyptians in street riots and protests under his rule.
More than 40 people were killed in January in clashes with security forces. A month earlier, 10 others were killed when supporters of the Muslim Brotherhood clamped down on anti-Morsi protesters staging a sit-in in front of the presidential palace. Several activists, arrested in street protests, were killed during torture.
But Bahgat noted that charges on those deaths would put the new leadership in a difficult position because it would also require indicting the current interior minister, in charge of police, who held the post under Morsi as well.
Instead, authorities are turning to "more politicized cases," said Bahgat, director of the Egyptian Initiative for Personal Rights. "All what is circulating now is more of a fiction than real."
"Now he is being held hostage to political negotiations and it depends on the deal, his fate will be decided."
Morsi's supporters have been holding protests and street marches nearly every day in Cairo in addition to sit-ins that have gone on for weeks in several cities. The marches have repeatedly turned violent, with dozens of mostly Morsi supporters killed.
Abdel-Sattar el-Meligi, a prominent former Brotherhood figure, said the group is hoping that protests can rally wider popular support. So far, however, "these are just very desperate attempts," he said.
"The Brotherhood failed to estimate the real anger in the street, the political weight of their opponents," he said. "The Brotherhood has exhausted all their credit in all levels."
On Monday, Essam el-Erian, deputy head of the Brotherhood's political party, urged protesters to "besiege" the U.S. Embassy and expel the ambassador, stepping up the group's accusations that Washington backed the coup. Morsi's opponents, in turn, accuse the U.S. of supporting his presidency.
Several hundred Islamists tried to march toward the U.S. Embassy hours later, passing near Tahrir Square, where Morsi opponents have been camped. Rock-throwing clashes erupted between the two sides, and gunshots were heard, though it was not clear who opened fire. Both sides were seen to have what appeared to be homemade pistols.
One Morsi opponent was killed and dozens of others wounded, some by birdshot and two by live ammunition, said George Ihab, a doctor at a field clinic set up by the anti-Morsi camp.
Several anti-Morsi demonstrators said the ousted president's supporters attacked their people guarding an entrance to Tahrir near a bridge over the Nile River.
"They attacked us from Qasr el-Nil Bridge with birdshot and live ammunition and molotovs," said Ahmed Korashi, whose hand was burned from what he said was a firebomb.
In a tweet, the Muslim Brotherhood denied its supporters attacked, saying its protests are peaceful.
Clashes also broke out in Qalioub, north of Cairo, when pro-Morsi protesters blocked a highway between the capital and the Mediterranean coastal city of Alexandria, security officials said. The security forces demanded the road be cleared, and protesters fired ammunition in the air. Clashes erupted with protesters throwing stones and security forces firing tear gas.
At least three people were killed, including a 15-year-old and an 18-year-old who died of gunshot wounds, the officials said, speaking on condition of anonymity because they were not authorized to talk to the press.
Security officials said the body of a 33-year-old textile worker, Amr Magdy Samak, was found near the sit-in with signs of torture. His body had bruises and his nails had been torn off, the officials said, adding that the death was under investigation.
In the Sinai Peninsula, suspected Islamic militants attacked security checkpoints in the town of Sheikh Zuweyid and the nearby city of el-Arish, killing a civilian and wounding three soldiers, security officials said. A string of militant attacks in the Sinai since Morsi's fall has killed 14 members of the security forces and several civilians.
___
Associated Press writer Raf Casert in Brussels contributed to this report.
Source: http://news.yahoo.com/ousted-egyptian-leaders-family-denounces-military-220013498.html
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Univision cancels talk show hosted by 'Piolin'
SANTA ANA, Calif. (AP) ? Radio listeners didn't hear a peep out of the animated Spanish-language personality nicknamed for "Tweety Bird" after Univision Radio Network yanked the talk radio host from the air, playing only music in his place.
Monica Talan, a Univision spokeswoman, confirmed Tuesday that the morning show "Piolin por la Manana," hosted by Eddie "Piolin" Sotelo, had been dropped. She declined to provide a reason.
For now, she said music will be played in the absence of the Mexican-born disc jockey, who urged his listeners to turn out for immigration reform events and pushed Hispanics to wield their clout in elections. He joined the station in 2004.
Sotelo rose to fame when he and other Spanish-language DJs used the airwaves in 2006 to propel immigrant supporters en masse into the streets of cities across the country to rally for immigrant rights.
Sotelo's program was peppered with pranks and jokes, but he also interviewed President Barack Obama and other politicians. He urged Hispanics to naturalize so they could vote, and became an American citizen himself at a 2008 ceremony teeming with media.
Javier Novoa, 50, said he liked the way Sotelo interviewed psychologists, immigration experts and financial gurus and imparted their wisdom to his audience. Novoa said he listened regularly to the program on his way to work selling CDs in downtown Santa Ana but lately found he was getting more music and less talk over the airwaves.
"It's surprising to me because this was a very good program. A lot of people listened to it," he said of the decision to pull Sotelo off the air.
For five of the last six months, Sotelo's show has lagged behind Ricardo "El Mandril" Sanchez's program in the Los Angeles-Orange County market's Arbitron ratings for morning shows. Both programs played regional Mexican music.
"El Mandril" was listed in the No. 1 spot in June, while Sotelo's program was No. 6, the ratings showed.
Dolores Ines Casillas, a professor of Chicana and Chicano studies at University of California, Santa Barbara, said she didn't think the ratings drop was significant enough for Sotelo's show to be cancelled.
She said Sotelo was extremely well-known and had been making television appearances in addition to radio. He also voiced roles in "Beverly Hills Chihuahua" and other movies.
"It happened so suddenly," said Casillas, who is writing a book about Spanish-language radio. "His show still was incredibly popular."
Sotelo, who grew up in Santa Ana, is expected to be inducted into the National Radio Hall of Fame in November. He often spoke of his own experience as an immigrant, crossing the border illegally in the 1980s, in an effort to inspire his listeners.
Immigrant advocates praised Sotelo for supporting the community in 2006 but said he didn't take on the issue as aggressively after the marches.
"He took time from his morning entertainment show to become the voice of the voiceless," said Jorge-Mario Cabrera, a spokesman for the Coalition for Humane Immigrant Rights of Los Angeles. "For that, we will always be thankful."
On Tuesday morning, the station played music and commercials. Sotelo could not immediately be reached for comment, and no updates were posted on his Facebook page or Twitter feeds.
___
Associated Press writer E.J. Tamara in Los Angeles contributed to this report.
Source: http://news.yahoo.com/univision-cancels-talk-show-hosted-piolin-220517403.html
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Turkey set to overshoot budget targets as elections approach
By Asli Kandemir
ISTANBUL (Reuters) - Turkey is likely to overshoot its budget deficit targets this year as the government spends in the run-up to elections to help keep the economy growing, economists said on Monday.
Prime Minister Tayyip Erdogan's government, which has built its reputation on Turkey's economic transformation over the past decade, is keen to maintain that record as it faces three elections in the next two years.
Growth this year is widely expected to fall short of a 4 percent government target with domestic demand remaining weak after falling sharply last year, private sector investment declining and the global environment offering little support.
The budget deficit-to-GDP ratio is expected to overshoot the government's 2.2 percent target as weaker growth reduces tax revenues and budget spending increases before the polls.
Weeks of anti-government protests coupled with concern about how much longer the U.S. Federal Reserve will pump out cheap money have prompted investors to pull billions of dollars out of Turkish capital markets since early May, leaving the country's gaping current account deficit exposed.
"Growth in the first quarter came almost totally from the public sector," said Elif Gulay Girgin, chief economist at Istanbul-based brokerage Ata Invest.
"It is estimated that in the second quarter, although there is as yet insufficient data, foreign markets and domestic developments had a slightly negative impact on the pick-up in private sector investments," she said.
In the first quarter gross domestic product (GDP) grew 3 percent, 2.9 percent of which was due to public spending. Private sector investment has failed to make a positive contribution to overall growth for the past four quarters.
"This trend will become more evident in the final quarter due to seasonal factors and the impact on public spending of the approaching elections," Girgin said, revising her growth forecast to 3.3 percent from 4 percent and her budget deficit-to-GDP forecast up to 2.6 percent from 2.4 percent.
RISKS TO BUDGET
Deputy Prime Minister Ali Babacan said last week that it should be "no surprise" if the government revises down its growth expectations for this year, but it needed more data from the second quarter and had no immediate plans to do so.
A Reuters poll of 25 economists last week, taken largely before the central bank indicated it could raise interest rates to prop up a weakening lira, showed median forecasts of growth picking up to just 3.7 percent this year.
After the economy grew 8.8 percent in 2011, the fastest in Europe, growth slowed sharply to 2.2 percent last year.
"At a time when youth unemployment is high, when there are serious downward risks to growth and there is a heavy election calendar, there are various risks on the budget front," Is Investment chief economist Burcu Unuvar said in a research note.
Unuvar said Is Investment had revised its 2013 growth forecast to 3.3 percent from 4 percent and expected a budget deficit-to-GDP ratio of 2.7 percent.
According to the latest finance ministry data, the budget showed a deficit of 1.2 billion lira ($615 million) in June, while the surplus in the first half amounted to 3.1 billion lira.
Budget expenditure rose 11.2 percent year-on-year to 187.9 billion lira in the first six months of the year, while revenues climbed 17.7 percent to 190.9 billion lira.
Turkey's budget expenditure generally increases sharply in the latter part of the year. The deficit last December was larger than for the rest of 2012 as a whole.
"It would not be surprising if the government resorts to expenditure-boosting policies before the long election period and this exerts pressure on fiscal balances," said Professor Umit Ozlale from Ozyegin University.
Last year, the government targeted a budget deficit of 1.5 percent but it ended the year at 2.3 percent due to increased expenditure, lower than expected privatization revenues and problems in the cash flow of state energy companies.
($1 = 1.9181 Turkish liras)
(Writing by Daren Butler; Editing by Nick Tattersall/Ruth Pitchford)
Source: http://news.yahoo.com/turkey-set-overshoot-budget-targets-elections-approach-164228477.html
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Tuesday, July 16, 2013
Google Glass enters a casino Watch what happens
Featured Story
The confetti was tossed and the bubbly was popped to celebrate New Zealand racing driver Scott Dixon's dominating victory at this weekend's IndyCar Championship here.
"Toronto has always been a place ...
Source: http://www.canadastandard.com/index.php/sid/215851560/scat/d805653303cbbba8
Monday, July 15, 2013
Munenori Kawasaki takes his antics on the fairway at Jays' charity golf tournament
Published Saturday, Jul 13, 2013 at 1:25 pm EDT Last updated 3 hours and 52 minutes ago
Munenori Kawasaki, the most outlandish, lovable man on the Blue Jays roster is best known for his antics on the field and in the sky.
He added another venue to his list this week, proving that the world truly is his stage.
At the Blue Jays' annual charity golf tournament, he used the fairway as his runway, striking this pose:
Then, he went on to rank his golf skills in comparison to his teammates during this interview with Canada SportsNet's Caroline Cameron.
Unfortunately, with Toronto activating Brett Lawrie from the DL, Kawasaki was optioned back to Triple-A Buffalo this morning but there's no doubt he'll continue to provide great entertainment.
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From Italian coast to U.S. desert, church leaders weigh in for migrants
WASHINGTON LETTER Jul-12-2013 (970 words) Backgrounder and analysis. With photos posted July 9 and 12. xxxn
From Italian coast to U.S. desert, church leaders weigh in for migrants
By Patricia Zapor
Catholic News Service
WASHINGTON (CNS) -- As pressure to pass an immigration reform bill shifted to the House of Representatives in July, the voices speaking out for more humane treatment of migrants included Pope Francis and former President George W. Bush.
Scores of advocates for comprehensive immigration reform swarmed over Capitol Hill day after day, visiting congressional offices and staging events such as a mock naturalization ceremony for would-be citizens who are currently in immigration limbo.
President Barack Obama met with the Congressional Hispanic Caucus one day and the next with two key senators, John McCain, R-Ariz., and Charles Schumer, D-N.Y. Both times the conversation was primarily about immigration reform, which Obama has made a high priority.
Meanwhile, a closed-door caucus of House Republicans July 10 was reported to have underscored just how the path to a comprehensive bill is overgrown with conflicting political interests.
House Republicans gave reporters varied versions of what they took away from the session.
House Speaker John Boehner of Ohio said the majority of his party's caucus members agree they need to address immigration, but that they prefer to do it piece-by-piece, focusing first on enforcement measures, rather than take up the comprehensive bill the Senate passed. Other Republicans said that while they want enforcement to come first, they might accept the legalization and citizenship path.
Still others, including Rep. Steve King of Iowa, were sticking to the notion that any path to legalization, even for people brought in as children who have no ties to another country, would destroy "the rule of law," as The New York Times reported. The Times said King conceded that support for his point in the caucus session was weaker than it has been in the past.
Backers of comprehensive reform, including the U.S. Conference of Catholic Bishops, a coalition of evangelicals and other faith groups argue that only by dealing with all the pieces of immigration -- border enforcement, legalization, fixes to the process for bringing in workers and family members and changes to requirements for verifying employee immigration status -- will any part of it work.
Meanwhile, Bush, in a rare public appearance in which he referenced public policy, at a naturalization ceremony urged Congress to take a broad approach to reform. He advocated for comprehensive reform when he was president.
In June, the Senate voted 68-32 for a bill that includes billions of dollars of new spending on border security and addresses a wide range of problems in the current systems, including: family immigration; various types of worker visas; and legal status for people who were brought to the U.S. as children. It includes a 13-year path to citizenship for many of the estimated 11 million immigrants who lack permission to be in the country. They would be required to speak English, pay fines and any taxes owed and meet other benchmarks.
Boehner and King, both Catholics, are among members of the House being targeted by a campaign set for the week of July 15. Dozens of Catholic university presidents planned to directly appeal to Catholics in the House to draw moral courage from their faith in supporting broad-based reform.
Those who ground their appeals for immigration reform in the teachings of Christianity about migrants got a timely and photogenic boost from Pope Francis July 8, as he visited Lampedusa, an Italian island where immigrants who try to reach Europe by sea are detained. He said he was moved to make the trip after he saw news stories describing the drowning of immigrants at sea.
"Those boats, instead of being a means of hope, were a means of death," he said.
In a homily given from a lectern built out of the hull and wheel of boats, the pope said he chose to make the Mass a penitential liturgy to "ask forgiveness for our indifference toward so many brothers and sisters" and for the ways in which well-being has "anesthetized our hearts."
The pope prayed for the forgiveness of "those, who with their decisions at the global level, have created situations that lead to these tragedies."
A couple of days later, Los Angeles Archbishop Jose H. Gomez compared those migrants lost at sea to those who die trying to start new lives in the United States by crossing the the border illegally.
In a statement, the chairman of the U.S. bishops' Committee on Migration said comprehensive reform of immigration laws in the U.S. would relieve the suffering of human beings, including due to "the separation of families, the exploitation of migrant workers and the death of our fellow human beings in the American desert."
Archbishop Gomez called on the House to pass "just and humane" immigration reform, adding that "the current immigration system, which causes so much human suffering, is a stain on the soul of our nation."
At a Social Action Summer Institute in Tucson, Ariz., a few weeks earlier, employees of Catholic parishes, dioceses and charitable organizations heard Holy Cross Father Daniel Groody, a theology professor at the University of Notre Dame, provide the theological context for the church's position on immigration.
Father Groody, who directs the Center for Latino Spirituality and Culture at the university's Institute for Latino Studies, spent many years doing pastoral work and research in Latin America and along the U.S.-Mexican border, particularly in the Coachella Valley of California.
He detailed the church's immigration-related teachings dating back to St. Thomas Aquinas' discussion of the kinds of rights people have, including the need to care for one's family and those defined in civil law.
The oft-voiced argument by proponents of harsh enforcement, "what part of illegal don't you understand," is "a great argument that has nothing to do with reality," Father Groody said, as he went on to detail ways in which God-given rights justifiably trump those of civil society.
END
Copyright (c) 2013 Catholic News Service/USCCB. All rights reserved.
This material may not be published, broadcast, rewritten or otherwise distributed.
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Source: http://www.catholicnews.com/data/stories/cns/1303031.htm
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Monday, June 10, 2013
Sunday, June 9, 2013
Israeli leader accuses Iran of cyberattacks
TEL AVIV, Israel (AP) ? Israel's prime minister said Sunday there has been a "significant rise" in cyberattacks on Israel by Iran.
Benjamin Netanyahu told a security conference that Iran, along with its proxies Hezbollah and Hamas, are targeting Israel's "essential systems." He said the water system, electric grid, trains and banks have all been targeted.
"Every sphere of civilian economic life, let's not even talk about our security, is a potential or actual cyberattack target," Netanyahu said. He said the attacks "will continue to intensify as we advance into the digital age."
Netanyahu gave no further details, and his office refused to elaborate.
Israeli officials have long said that the country is under constant attack by enemies and ideological opponents to shut down vital websites. Most attacks have had little impact.
Shlomi Dolev, a cybersecurity expert at Israel's Ben-Gurion University, said it is logical to assume that Iran is trying to attack Israeli targets. He said Israel is under constant threat, though he could not verify the sources.
"I'm not sure how sophisticated they are. But they of course have some experts," Dolev said.
Israel considers Iran to be its most dangerous enemy, citing Tehran's support for Arab militant groups, its years of hostile anti-Israel rhetoric and its suspect nuclear program. Israel, like many Western countries, believes Iran is trying to develop a nuclear bomb.
Israel is a world leader in cyber security, thanks in large part to expertise developed in shadowy high-tech units in the military. Israel is widely expected of launching sophisticated computer attacks on its enemies, including a worm that targeted Iran's nuclear program and caused significant damage.
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Equipment operator to be charged in Pa. building collapse
PHILADELPHIA (AP) ? A felon who was allegedly high while operating demolition equipment when a downtown building collapsed and killed six people will be charged with involuntary manslaughter, a top city official said Friday.
Sean Benschop, 42, faces six manslaughter counts along with six counts of risking a catastrophe, six counts of reckless endangerment and other charges, Deputy Mayor Everett Gillison told The Associated Press.
Authorities believe Benschop had been using an excavator Wednesday when what was left of the four-story building gave way and fell on top of a neighboring Salvation Army thrift store, killing two employees and four customers, and injuring 13 others.
A toxicology report showed "evidence that he was high" on marijuana, Gillison said. That finding, combined with witness statements and evidence from the scene, led to the decision Friday to raid his North Philadelphia home and later seek an arrest warrant, he said.
"The D.A. has approved it (his arrest), and my police officers are out looking for him as we speak," said Gillison, the deputy mayor for public safety.
Benschop, who also goes by the name Kary Roberts, has been arrested at least 11 times since 1994 on charges ranging from drugs to theft to weapons possession, according to court records. He was twice sentenced to prison in the 1990s after being convicted on drug trafficking charges. Benschop's last arrest, for aggravated assault, came in January 2012, but the case was dismissed for lack of evidence.
Benschop did not return phone messages left at numbers listed in his name, though he told The Philadelphia Inquirer on Thursday that he couldn't comment because of the investigation.
The victims include a pair of 24-year-old artist friends shopping at the store and a newly engaged woman working her first day there.
Video shot of the scene days before the fatal collapse showed bricks falling onto a sidewalk, which remained open to pedestrians, as a worker used heavy equipment to take out a front wall.
Some blame has been lobbed at demolition contractor Griffin Campbell, whose background includes arrests for drugs, assault and insurance fraud, along with two bankruptcy filings. He was being paid $10,000 for the job, according to the demolition permit.
Campbell violated several federal safety regulations, while building owner Richard Basciano should have picked a more qualified and competent contractor to do the work, said lawyer Robert Mongeluzzi, who represents injured store worker Nadine White in a lawsuit filed against the pair.
"From what we can understand, given (Campbell's) checkered past, and what appears to be a total lack of experience and know-how, we believe that was a grossly negligent selection," said Mongeluzzi, who won court permission Friday to examine the debris after city officials finish their investigation.
The collapse has brought swift and mounting fallout in a city where demolition contractors are lightly regulated. Officials have begun inspecting hundreds of demolition sites citywide, and a city councilman charged that dangerous, under-the-radar tear-downs are taking place throughout Philadelphia.
The city is preparing to implement sweeping changes in its regulations of building demolition, Mayor Michael Nutter said Friday, adding that every active demolition site is being inspected for safety.
The mayor appeared forlorn at the afternoon news conference at City Hall, apologizing to the victims' families for the deaths and promising the city would do better.
"We lack the resources to have a police officer on every corner, or L&I (License and Inspections) at every construction site every hour of the day, (but) we can do much better," Nutter said. "We will not accept the status quo in the face of this tragedy."
Nutter's reform plan for construction sites that includes the random drug testing of heavy equipment operators.
"If that's a factor here, that certainly takes things in a very different direction," Nutter said hours before the charges were confirmed.
The mayor also pledged to adopt tougher background requirements for demolition contractors, including information about each worker's experience, and more frequent site inspections when demolitions are underway.
Construction engineers have said adjacent buildings should be evacuated during critical phases of a demolition project. The other victims also include two immigrants from Africa, a 68-year-old man from Liberia described as a devoted husband and Salvation Army worker, and a 52-year-old woman from Sierra Leone who had nine children and loved to hunt for bargains.
The Salvation Army was concerned enough about the demolition that its attorneys reached out to a lawyer for building owner STB Investments Corp., a company linked to prominent businessman and developer Richard Basciano.
"There was communication between The Salvation Army and the attorney of the neighboring building's owner, pertaining to the demolition. The neighbor assured The Salvation Army that they would be taking proper precautions," Maj. Robert W. Dixon, director of operations of The Salvation Army of Greater Philadelphia, said in a statement Friday afternoon.
"These discussions were never finalized," he said.
___
Rubinkam reported from northeastern Pennsylvania. Associated Press writers JoAnn Loviglio, Kevin Begos and Keith Collins contributed to this report, along with AP's News and Information Research Center.
Source: http://news.yahoo.com/equipment-operator-charged-pa-collapse-224153913.html
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88% Upstream Color
All Critics (81) | Top Critics (28) | Fresh (71) | Rotten (10) | DVD (1)
A cerebral, mournful mystery that resonates like a tuning fork struck on a far-off star.
It presents us with a glimpse of the vastness of existence, of our inner nature, and of nature without that is as equally dreadful, enveloping, and terrifying as it is beautiful.
"Upstream Color" is splendid, transcendent weirdness.
Sci-fi might have been too familiar a word, for what may induce a kind of hallucinatory melancholy in its viewers.
Elliptical and utterly fascinating adventure in cinema, one that defies simple explanations, but worms its way into the brain.
Carruth's complex and muted thriller is exquisitely made and acted. It's a film that challenges the viewer provoking fine existential questions.
No, there aren't any extras to speak of, and it doesn't matter. Shane Carruth's mesmerizing fantasy is still a must-own.
May represent a milestone in modern indie cinema, or at least a steppingstone between the smart microbudget work signified by star Amy Seimetz and the more grandiose aspirations associated with someone like -- dare I invoke the name? -- Stanley Kubrick.
Very few movies actually invite us in, meet us halfway, or offer us something. Upstream Color does that in such a unique, singular way that it's unlike almost any other movie I've ever seen.
Those who require a beating pulse to set the tempo for jigsaw puzzle moviegoing are hereby warned, as Carruth isn't interested in making things easy. He wants to squeeze your mind, not hold your hand.
It's not designed to stump or baffle but to beckon you into its wondrously chilly gray world. If it takes a few viewings to unlock (most of) its secrets then lucky you; you spent high-quality time you might have wasted on Pain & Gain.
If Shane Carruth's time-traveling debut Primer was about outthinking what you might do in the future, his second movie, Upstream Color, is about deciphering why you feel the way you do right now.
I have no idea what it was about, and I can't wait to see it again.
My immediate desire when it ended was to stay in my seat and watch it all the way through again.
Swooning, frightening, intoxicating, and a cinematic experience that feels genuinely new.
...works on its own idiosyncratic wavelength, one that isn't alienating, but isn't quite approachable either.
Its plot isn't particularly complicated, but it is undeniably weird. if you accept the movie on its own terms, you'll feel like you've been pulled into a creepy yet compelling dream.
Shane Carruth continues to grow as a filmmaker even as he remains keen to puzzle and perhaps frustrate. Upstream Color is, above all else, an unforgettable experience.
I found it one of the most invigorating and intoxicating movie experiences of the year.
There's some sort of genius buried within Upstream Color, but it's so enigmatic and obscure that by the time you reach it after digging through its countless layers you'll likely never find your way back again.
Source: http://www.rottentomatoes.com/m/upstream_color/
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Friday, May 24, 2013
Historian hopes to clear Union colonel?s name in observance of Darien?s burning ? Florida Times
Robert Gould Shaw, the Union Army colonel maligned for burning the coastal town of Darien during the Civil War, was following orders and doesn?t deserve the reputation he has borne for a century and a half.
That?s one wrong McIntosh County historian Buddy Sullivan wants to right as the 150th anniversary of the town?s burning approaches.
?It?s a great misconception,? he said. ?Everyone assumed Shaw was the one that burned Darien, especially since the movie ?Glory? came out.?
Matthew Broderick played the white Shaw in the 1989 movie about the otherwise all-black 54th Massachusetts Regiment. It was actually his superior officer, Col. James Montgomery of the 2nd South Carolina Volunteers, who ordered the attack, Sullivan said.
?Shaw reluctantly carried out the raid under threat of court-martial,? Sullivan said.
The burning took place on June 11, 1863, and Darien will commemorate it with a town festival on Saturday, June 15, from 10 a.m. until 5 p.m.
The festival will feature a living history encampment by the 54th Massachusetts re-enactment group out of Charleston, S.C., as well as the usual festival food and arts and crafts vendors, Fort King George Historic Site Park Ranger Jason Baker said.
The re-enactors will simulate camp life as it was during the war, Baker said.
?They?ll be sitting around in their uniforms with their muskets, talking soldier talk,? he said. ?It will be like a day in the life of a Union soldier.?
Sullivan will provide commentary during three one-hour boat tours piloted by Capt. Phillip Kempton along the Darien River from the town?s waterfront park to Fort King George and back.
?It?ll be free of charge on a first-come first-served basis,? Sullivan said.
Shaw wrote his mother, Sarah Blake Shaw, and wife, Anna Haggerty Shaw, after the raid, expressing his remorse for an operation he considered unnecessary, Sullivan said. Shaw?s survivors set about restoring his reputation after his death.
?The great irony is Shaw lost his life about a month later leading his troops in the assault of Fort Wagner near Charleston,? Sullivan said.
Sarah Blake Shaw, an Episcopalian, helped fund the rebuilding of St. Andrews Episcopal Church, which was burned in the raid, Sullivan said.
But her efforts to restore her son?s reputation failed, Sullivan said.
?I remember growing up in McIntosh County and hearing older people refer to the burning of Darien,? he said. ?It was the low point in Darien history and Shaw was always thought of as the villain.?
Leading up to the commemoration, Sullivan will present a lecture about the town?s burning on June 9 at St. Cyprian?s Episcopal Church.
He will attempt to correct one other misconception, that the town?s burning was part of Gen. William T. Sherman?s infamous March to the Sea.
Sherman?s march from Atlanta to Savannah occurred in November-December 1864, 18 months after Darien was torched.
On June 11, the actual anniversary of the burning, The Burning of Darien Civil War Museum will open at the Trailhead Center, and on June 20, University of Georgia history professor Stephen Berry will talk about Sherman?s march at Fort King George.
For more information, visit the website www.burningofdarien.com.
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Thursday, May 23, 2013
Japan hospital tests powerful breast cancer therapy | Capital News
Doctors in a cancer radiation room/FILE
TOKYO, May 22 ? A Japanese cancer specialist said Wednesday she has started the world?s first clinical trial of a powerful, non-surgical, short-term radiation therapy for breast cancer.
The National Institute of Radiological Sciences has begun the trial using ?heavy ion radiotherapy? which emits a pinpoint beam that can be accurately directed at malignant cells, said Kumiko Karasawa, radiation oncologist and breast cancer specialist.
The study was launched amid renewed global interest in breast cancer and its treatment after Oscar-winning actress Angelina Jolie revealed she had undergone a preventative double mastectomy.
Heavy ion radiotherapy has proved effective in combating other forms of cancer that have not spread, Karasawa said.
?We are able to conduct this trial because we have greater understanding of what types of breast cancer can benefit from this pinpoint treatment,? Karasawa told AFP.
Development of medical apparatus that keeps soft breast tissue immobile for this treatment has also helped, she added.
Japan is a leader in the technology used in the treatment, and is home to three of the world?s six medical centres that have the gigantic 10-billion-yen ($97.2 million) facilities, Karasawa said.
The therapy has proved its worth on other forms of cancer, including prostate and lung, Kyodo News said, but has never before been used on breast cancer.
Conventional radiotherapy uses X-rays and gamma rays that are most potent at the surface of the body, but weaken as they travel deeper into the tissue.
Heavy ion particle beams maintain their strength to a much greater depth.
In the trial, Karasawa will treat a total of 20 patients aged at least 60 and with small tumours that have not spread.
The patients will go through an hour of therapy per day for four days, much shorter than conventional radiation therapy that may last for months, Karasawa said.
The trial will follow the patients for five years to assess the outcome, she said.
?Ultimately, this could provide an option for patients who do not want surgery and who cannot go through (common radiation therapy) requiring regular visits to clinics for months,? she said.
Japan, which has a high-quality medical system, has a good track record with breast cancer, giving patients a 90 percent five-year survival rate.
Localised and less invasive medical treatments are increasingly important as ageing Japan tries to reduce the physical burden for patients, the national institute said in a statement.
Source: http://www.capitalfm.co.ke/news/2013/05/short-term-radiation-therapy-for-breast-cancer-launched/
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Paris Hilton Joins Lil Wayne's Cash Money Family?
Heiress says she's signed to Weezy's label and will focus on house music on her summer sophomore album.
By Jocelyn Vena
Paris Hilton
Photo: Jason Merritt/ Getty Images
Source: http://www.mtv.com/news/articles/1707867/paris-hilton-signs-to-cash-money-lil-wayne.jhtml
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Group Therapy: I'm two months into my marriage and I feel nothing.
The passion/lust/romance? There is none.
?
?
?
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By ANONYMOUS
My husband and I hit it off from the first moment we met (at work). We were finishing each others sentences in a weird mind-reading way after knowing each other only one day.
He was married but separated when we met and while that hasn?t caused a single problem (apart from the debt he brought to the relationship ? I had none) and his ex-wife can now be the single career orientated person she really wants to be.
As for our working life, well that?s just fun and games. We work in the same industry and same place but he is the boss. Given our working hours and the job we do, I barely see him at work let alone have a conversation. I actually prefer that so no one can say there is favouritism or preferential treatment occurring.
When not at work I see him for 30 minutes in the morning and a couple of hours in the evening but we never do anything as we are both exhausted! He does make me cups of tea for which I love him dearly.
As for the passion/lust/romance? Well there is none. At least from my side.
I feel nothing. I feel flat. Pancakes probably have a better love life. I do love my husband. Well I think I do. I?d never been in love before so I have nothing to compare it to. We have been together nearly two years and married for two months.
Prior to meeting my DH my longest relationship was 10 months. I had lots of, shall we say, short term relationships beforehand. I know that if anything happened to my DH I would be devastated. I do miss him if he is away (but not in a sooky weepy way) so I know there is an emotional attachment there.
This? Doesn?t happen?
But why why why do I feel no passion? Sex feels like too much hard work. I?m quite happy to starfish it. He wants more I know but is happy with what he gets and understands I?m tired/stressed/lacking hormones.
I am not turned off by him. He is not ugly. He doesn?t have bad teeth or BO but he has let himself go a bit and has put on weight, whereas I?m doing my hardest to lose it.
He would do anything I ask but still I feel nothing. I try hard to figure out what is wrong. I changed pill, came off the pill, had blood tests and took antidepressants? and still nothing.
Work doesn?t help. It?s stressful and tiring. Shift work means you have few or zero friends who are not shift workers (they don?t understand when you work weekends and evenings) so our social life is crap. We moved to a country town to be near my mother after my father died (I moved back from London before I met my DH so I miss it dreadfully too).
I do know that I want to be with him. I am happy but sad at the same time.
And he has no idea.
The author of this post is known to Mamamia but has chosen to remain anonymous.
Have you got any advice or support you can offer Anonymous?
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Sony 32GB 94MB/s SDHC Memory Card: $30 Shipped (Or 8GB: $10,16GB: $17)
Adorama Camera?has the?Sony 32GB Class 10 SDHC UHS-1 Memory Card, 94 MB/s Read Speed $30 shipped, most other retailers price it at $40 while the MSRP is $50. ?Reviewers speak highly of the cards? super fast speeds, allowing photographers to load images into Lightroom quicker and snap the perfect photo without any hangups. ?94MB/sec is nearly as fast as SATA SSD speeds. ?You can also pickup this card in a 8GB ($10)?or?16GB?($17)?flavors.
Also available on Amazon via Adorama.
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Samsung 250GB 840 Series SATAIII 2.5 inch Solid State Drive (SSD) $142 +?Shipping
Philips Unleashes a Stunning 29? Panoramic HD Monitor w/ Simultaneous Dual Input?Support
Source: http://feedproxy.google.com/~r/9to5macToys/~3/ZjGluPgvDcs/
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Going green: Nation equipped to grow serious amounts of pond scum for fuel
Wednesday, May 22, 2013
A new analysis shows that the nation's land and water resources could likely support the growth of enough algae to produce up to 25 billion gallons of algae-based fuel a year in the United States, one-twelfth of the country's yearly needs.
The findings come from an in-depth look at the water resources that would be needed to grow significant amounts of algae in large, specially built shallow ponds. The results were published in the May 7 issue of Environmental Science and Technology, published by the American Chemical Society.
"While there are many details still to be worked out, we don't see water issues as a deal breaker for the development of an algae biofuels industry in many areas of the country," said first author Erik Venteris of the Department of Energy's Pacific Northwest National Laboratory.
For the best places to produce algae for fuel, think hot, humid and wet. Especially promising are the Gulf Coast and the Southeastern seaboard.
"The Gulf Coast offers a good combination of warm temperatures, low evaporation, access to an abundance of water, and plenty of fuel-processing facilities," said hydrologist Mark Wigmosta, the leader of the team that did the analysis.
Wooing algae as fuel
Algae, it turns out, are plump with oil, and several research teams and companies are pursuing ways to improve the creation of biofuels based on algae ? growing algae composed of more oil, creating algae that live longer and thrive in cooler temperatures, or devising new ways to separate out the useful oil from the rest of the algae.
But first, simply, the algae must grow. The chief requirements are sunlight and water. Antagonists include clouds, a shortage of water, and evaporation.
A previous report by the same team looked mainly at how much demand algae farms would create for freshwater. That report demonstrated that oil based on algae have the potential to replace a significant portion of the nation's oil imports and drew the attention of President Obama.
The new report focuses on actual water supplies and looks at a range of possible sources of water, including fresh groundwater, salty or saline groundwater, and seawater. The team estimates that up to 25 billion gallons of algal oil could be produced annually, an increase of 4 billion gallons over the previous study's estimate. The new amount is enough to fill the nation's current oil needs for one month ? about 600 million barrels ? each year. The study's authors note that the new estimate is exactly that ? an estimate ? based to some degree on assumptions about land and water availability and use.
"I'm confident that algal biofuels can be part of the solution to our energy needs, but algal biofuels certainly aren't the whole solution," said Wigmosta. Most important, he notes that the cost of making the fuel far exceeds the cost of traditional gasoline-based products right now.
Big ponds, big potential
An algae farm would likely consist of many ponds, with water maybe six to 15 inches deep. A few companies have built smaller algae farms and are just beginning to churn out huge amounts of algae to convert to fuel; earlier this year, one company sold algae-based oil to customers in California. Players in the algae biofuels arena range from Exxon-Mobil, which launched a $600 million research effort four years ago, to this year's teenage winner of the Intel Science Talent Search, who was recognized for her work developing algae that produce more oil than they normally do.
The availability of water has been one of the biggest concerns regarding the adoption of broad-scale production of algal biofuel. Scientists estimate that fuel created with algae would use much more water than industrial processes used to harness energy from oil, wind, sunlight, or most other forms of raw energy. To produce 25 billion gallons of algae oil, the team estimates that the process annually would require the equivalent of about one-quarter of the amount of water that is now used each year in the entire United States for agriculture. While that is a huge amount, the team notes that the water would come from a multitude of sources: fresh groundwater, salty groundwater, and seawater.
For its analysis, the team limited the amount of freshwater that could be drawn in any one area, assuming that no more than 5 percent of a given watershed's mean annual water flow could be used in algae production. That number is a starting point, says Venteris, who notes that it's the same percentage that the U.S. Environmental Protection Agency allows power plants to use for cooling.
"In arid areas such as the Desert Southwest, 5 percent is probably an overstatement of the amount of water available, but in many other areas that are a lot wetter, such as much of the East, it's likely that much more water would be available," says Venteris.
"While the nation's Desert Southwest has been considered a possible site for vast algae growth using saline water, rapid evaporation in this region make success there more challenging for low- cost production," Venteris added.
Venteris and colleagues weighed the pluses and minuses of the various water sources. They note that freshwater is cheap but in very limited supply in many areas. Saline groundwater is attractive because it's widely available but usually at a much deeper depth, requiring more equipment and technology to pump it to the surface and make it suitable for algae production. Seawater is plentiful, but would require much more infrastructure, most notably the creation of pipelines to move the water from the coast to processing plants.
The team notes that special circumstances, such as particularly tight water restrictions in some areas or severe drought or above-average rainfall in others, could affect its estimates of water availability.
###
DOE/Pacific Northwest National Laboratory: http://www.pnnl.gov/news
Thanks to DOE/Pacific Northwest National Laboratory for this article.
This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.
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Wednesday, May 22, 2013
Overcoming resistance to anti-cancer drugs by targeting cell 'powerhouses'
![[ Back to EurekAlert! ]](http://www.eurekalert.org/images/back2e.gif){kind=small}
Public release date: 22-May-2013[ | E-mail |
Share ] Contact: Michael Bernstein
m_bernstein@acs.org
202-872-6042
American Chemical Society
Re-routing anti-cancer drugs to the "power plants" that make energy to keep cells alive is a promising but long-neglected approach to preventing emergence of the drug-resistant forms of cancer source of a serious medical problem, scientists are reporting. That's the conclusion of a new study published in the journal ACS Chemical Biology.
Shana Kelley and colleagues explain that doxorubicin and other common forms of chemotherapy work by damaging the genes inside the nucleus of cancer cells. Cancer cells divide and multiply faster than surrounding normal cells, making copies of their genes. The drugs disrupt that process. But cancer cells eventually adapt, developing structures that pump out nucleus-attacking drugs before they can work. Kelley's team explored the effects of targeting doxorubicin to the mitochondria, the energy-producing structures in cells that also contain genes.
They describe a re-targeting approach that involved mating doxorubicin with a small piece of protein that made the drug travel to mitochondria instead of the nucleus. The combo killed cancer cells, even those that had developed pumps. Such an approach could work with a whole family of anti-cancer drugs that target the nucleus, the scientists indicate.
###
The authors acknowledge funding from the Canadian Institutes of Health Research.
The American Chemical Society is a nonprofit organization chartered by the U.S. Congress. With more than 163,000 members, ACS is the world's largest scientific society and a global leader in providing access to chemistry-related research through its multiple databases, peer-reviewed journals and scientific conferences. Its main offices are in Washington, D.C., and Columbus, Ohio.
To automatically receive news releases from the American Chemical Society, contact newsroom@acs.org.
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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Public release date: 22-May-2013[ | E-mail |
Share ] Contact: Michael Bernstein
m_bernstein@acs.org
202-872-6042
American Chemical Society
Re-routing anti-cancer drugs to the "power plants" that make energy to keep cells alive is a promising but long-neglected approach to preventing emergence of the drug-resistant forms of cancer source of a serious medical problem, scientists are reporting. That's the conclusion of a new study published in the journal ACS Chemical Biology.
Shana Kelley and colleagues explain that doxorubicin and other common forms of chemotherapy work by damaging the genes inside the nucleus of cancer cells. Cancer cells divide and multiply faster than surrounding normal cells, making copies of their genes. The drugs disrupt that process. But cancer cells eventually adapt, developing structures that pump out nucleus-attacking drugs before they can work. Kelley's team explored the effects of targeting doxorubicin to the mitochondria, the energy-producing structures in cells that also contain genes.
They describe a re-targeting approach that involved mating doxorubicin with a small piece of protein that made the drug travel to mitochondria instead of the nucleus. The combo killed cancer cells, even those that had developed pumps. Such an approach could work with a whole family of anti-cancer drugs that target the nucleus, the scientists indicate.
###
The authors acknowledge funding from the Canadian Institutes of Health Research.
The American Chemical Society is a nonprofit organization chartered by the U.S. Congress. With more than 163,000 members, ACS is the world's largest scientific society and a global leader in providing access to chemistry-related research through its multiple databases, peer-reviewed journals and scientific conferences. Its main offices are in Washington, D.C., and Columbus, Ohio.
To automatically receive news releases from the American Chemical Society, contact newsroom@acs.org.
Follow us: Twitter Facebook
[ | E-mail | Share ] ?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Source: http://www.eurekalert.org/pub_releases/2013-05/acs-ort052213.php
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